Fig. 3
From: Efficacy and local irritation evaluation of Eriobotrya japonica leaf ethanol extract

The effects of EJEE on cell viability (a) and melanin contents (b). The cells were treated different concentrations (0.01, 0.05, 0.1, 0.5, and 1.0%) of EJEE for 24 h. The basal values (control) were obtained in the absence of EJEE. **p < 0.01 as compared to the control group (a). The cells were treated with α-MSH (100 nM) and different concentrations (0.01, 0.05, and 0.1%) of EJEE for 72 h. Arbutin (10 mM) was used as a positive control. The values represent as the means ± SD of three independent experiments. *p < 0.05 as compared to the α-MSH-treated group (b)