Fig. 2
From: Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine
Weight and motor performance. a: Weight of aged mice was significantly higher than that of young mice (32.8 ± 5.4 g versus 23.2 ± 3.4 g; p < 0.0001). Weight of surviving and deceased aged mice did not differ (33.3 ± 5.0 g versus 30.2 ± 7.5 g; p = 0.30). Data are presented as individual values and means and were compared using Student’s t-test (***p < 0.0001; ns = not significant). b: Tight rope test scores [medians (25th percentile/75th percentile)] of aged mice were significantly higher than those of young mice [16(9.75/18.25) versus 1(1/2); p < 0.0001]. Tight rope test scores of surviving and deceased aged mice did not differ [16(10/18.25) versus 11(2.5/19.5); p = 0.83]. Data are presented as individual values and medians and were compared using the Mann-Whitney U-test (***p < 0.0001; ns = not significant)