Table 2 Hematological analysis of Korl:ICR, A:ICR and B:ICR with BoNT/A muscle treatment

No. of animals

10

10

10

10

10

10

RBC (10⁶/ul)

10.55 ± 0.44

9.10 ± 0.27^**

10.50 ± 0.25

8.61 ± 0.58^**

10.72 ± 0.24

8.72 ± 0.25^**

HGB (g/dl)

15.67 ± 0.71

14.67 ± 0.58^**

15.58 ± 0.33

13.98 ± 0.75^**

15.79 ± 0.44

14.26 ± 0.36^**

HCT (%)

50.93 ± 1.77

47.94 ± 1.76^**

49.21 ± 1.04

46.15 ± 2.61^**

50.55 ± 1.13

46.44 ± 1.07^**

MCV (fL)

48.32 ± 0.92

52.70 ± 1.47^**

46.88 ± 0.40

53.61 ± 1.36^**

47.16 ± 0.37

53.30 ± 1.40^**

MCH (pg)

14.86 ± 0.20

16.14 ± 0.66^**

14.84 ± 0.16

16.26 ± 0.58^**

14.72 ± 0.14

16.28 ± 0.37^**

MCHC (g/dl)

30.79 ± 0.79

30.64 ± 0.68

31.64 ± 0.35

30.31 ± 0.45^**

31.25 ± 0.38

30.69 ± 0.41^**

PLT (10³/ul)

1117.70 ± 134.98

1276.30 ± 184.56

1065.00 ± 200.56

1505.10 ± 179.39^**

1107.60 ± 122.23

1275.50 ± 193.77^**

WBC (10³/ul)

2.23 ± 0.85

2.58 ± 0.80

2.62 ± 0.77

4.98 ± 1.28^**

1.48 ± 0.28

3.38 ± 1.11^**

 Neutrophil (10³/ul)

0.33 ± 0.09

0.43 ± 0.14

0.37 ± 0.08

0.74 ± 0.51

0.25 ± 0.05

0.51 ± 0.13

 Lymphocyte (10³/ul)

1.57 ± 0.48

1.94 ± 0.64

2.11 ± 0.65

3.95 ± 1.27^**

1.15 ± 0.16

2.59 ± 0.87

 Monocyte (10³/ul)

0.03 ± 0.01

0.05 ± 0.02

0.04 ± 0.01

0.08 ± 0.02^**

0.03 ± 0.01

0.08 ± 0.02

 Eosinophil (10³/ul)

0.05 ± 0.02

0.12 ± 0.06

0.07 ± 0.02

0.13 ± 0.09

0.06 ± 0.01

0.14 ± 0.18

 Basophil (10³/ul)

0.01 ± 0.01

0.02 ± 0.01

0.01 ± 0.01

0.02 ± 0.01^**

0.01 ± 0.01

0.02 ± 0.01

 Neutrophil (%)

15.98 ± 4.76

17.09 ± 4.87

14.42 ± 1.43

15.19 ± 9.47

16.89 ± 2.74

15.87 ± 4.26^**

 Lymphocyte (%)

72.13 ± 10.14

74.57 ± 4.76

79.99 ± 2.02

78.71 ± 9.55

77.60 ± 11.75

76.14 ± 4.41^**

 Monocyte (%)

1.40 ± 0.70

2.05 ± 0.50

1.48 ± 0.24

1.58 ± 0.43

1.80 ± 0.88

2.32 ± 0.31^**

 Eosinophil (%)

2.31 ± 1.46

4.40 ± 1.86

2.68 ± 0.45

2.94 ± 2.32

4.02 ± 1.66

3.65 ± 3.10

 Basophil (%)

0.55 ± 0.28

0.58 ± 0.29

0.47 ± 0.22

0.48 ± 0.18

0.79 ± 0.36

0.60 ± 0.25

 Reti (10³/ul)

339.60 ± 30.29

318.06 ± 148.94

341.60 ± 25.56

331.18 ± 58.50

325.71 ± 28.23

355.47 ± 53.07

 Reti (%)

3.23 ± 0.37

3.51 ± 1.65

3.26 ± 0.27

3.88 ± 0.87

3.04 ± 0.20

3.84 ± 0.55^**