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Table 3 Serum biochemistry analysis of Korl:ICR, A:ICR and B:ICR with BoNT/A muscle treatment

From: Comparison study of the response with botulinum toxin muscle injection in the ICR mice from three different sources

Parameters/Groups

Con-Korl:ICR

Treated-Korl:ICR

Con-A:ICR

Treated-A:ICR

Con-B:ICR

Treated-B:ICR

No. of animals

10

10

10

10

10

10

Na (mmol/L)

159.19 ± 0.79

152.95 ± 1.28**

156.24 ± 1.06

150.09 ± 2.05**

157.43 ± 1.2

153.16 ± 1.96**

K (mmol/L)

7.00 ± 0.05

5.65 ± 0.71**

6.78 ± 0.04

6.91 ± 0.55

6.90 ± 0.08

6.74 ± 0.83

CL (mmol/L)

117.81 ± 0.46

115.75 ± 3.07

115.77 ± 0.84

107.91 ± 2.57**

116.35 ± 1.06

111.12 ± 1.36**

TP (g/dL)

5.35 ± 0.05

5.44 ± 0.30

5.28 ± 0.04

5.19 ± 0.34

5.28 ± 0.06

5.23 ± 0.37

ALB (g/dL)

3.29 ± 0.03

3.41 ± 0.18

3.14 ± 0.19

3.19 ± 0.20

3.21 ± 0.03

3.14 ± 0.22

BUN (mg/dL)

20.70 ± 0.20

18.54 ± 3.55

20.36 ± 0.13

18.64 ± 3.60

20.43 ± 0.23

20.18 ± 1.96

CRE (mg/dL)

0.38 ± 0.04

0.30 ± 0.07**

0.39 ± 0.03

0.33 ± 0.05**

0.40 ± 0.00

0.30 ± 0.05**

GLU (mg/dL)

164.30 ± 0.95

152.80 ± 22.24

161.10 ± 1.29

210.50 ± 23.90**

161.60 ± 1.96

159.90 ± 13.86

TBIL (mg/dL)

0.01 ± 0.00

0.05 ± 0.05

0.01 ± 0.00

0.04 ± 0.05**

0.01 ± 0.00

0.05 ± 0.05

Ca (mg/dL)

10.12 ± 0.06

9.96 ± 0.41

9.98 ± 0.09

9.95 ± 0.41

10.02 ± 0.12

10.07 ± 0.45

PHOS (mg/dL)

8.62 ± 0.04

9.38 ± 1.10

8.47 ± 0.07

10.12 ± 1.06**

8.50 ± 0.08

9.11 ± 0.58**

TCHOL (mg/dL)

133.10 ± 0.74

108.10 ± 17.15**

130.60 ± 1.17

122.40 ± 13.79

131.20 ± 1.32

137.70 ± 28.72

TG (mg/dL)

127.80 ± 1.48

43.80 ± 19.56**

132.00 ± 1.41

104.40 ± 31.73

129.80 ± 1.32

108.60 ± 29.96

AST (U/L)

144.60 ± 0.70

140.40 ± 119.47

141.80 ± 1.40

86.50 ± 62.67

142.80 ± 1.03

70.40 ± 38.61**

ALT (U/L)

49.40 ± 0.52

36.40 ± 8.37**

48.50 ± 0.53

41.60 ± 19.59

48.60 ± 0.52

35.80 ± 10.96**

ALP (U/L)

501.10 ± 2.33

384.10 ± 87.26**

492.80 ± 4.08

370.10 ± 95.19**

494.80 ± 4.26

326.00 ± 84.85**

HDL (mg/dL)

120.50 ± 0.97

95.70 ± 14.01**

117.20 ± 1.23

103.90 ± 11.75**

118.80 ± 1.14

119.80 ± 24.47

LDL (mg/dL)

11.50 ± 0.18

19.35 ± 4.30**

11.46 ± 0.46

16.83 ± 4.38**

11.56 ± 0.20

16.81 ± 8.31

PL (mg/dL)

251.20 ± 3.88

189.80 ± 26.86**

255.00 ± 5.03

228.20 ± 21.76**

252.90 ± 3.87

256.20 ± 41.74

hsCRP (mg/dL)

0.01 ± 0.00

0.01 ± 0.00

0.01 ± 0.01

0.01 ± 0.00

0.01 ± 0.01

0.01 ± 0.01

  1. The data shown represent the mean ± SD (n = 10/group)
  2. *Significantly different from the negative control group (*p < 0.05, **p < 0.01). The data represent the mean ± SD