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Fig. 2 | Laboratory Animal Research

Fig. 2

From: Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources

Fig. 2

Comparative analysis of nigrostriatal dopamine susceptibility to acute MPTP administration among different stocks of C57BL/6 mice. a Dose-dependent changes in dopamine concentration in the substantia nigra (SN) and (b) striatum (STR) regions. Values presented are mean ± SD; each group consisted of 5–6 mice. Different letters indicate a significant difference (p < 0.05) among treatments within mouse stocks (a denotes statistical significance compared to control group, b denotes statistical significance compared to MPTP 10 group, and c denotes statistical significance compared to MPTP 20 group)

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