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Fig. 4 | Laboratory Animal Research

Fig. 4

From: Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources

Fig. 4

Histopathological and quantitative analysis of tyrosine hydroxylase (TH) expression under acute MPTP administration among different C57BL/6 stocks. a Representative immunofluorescence images showing TH in SN and STR regions. Magnification of all images is 20×. b and c Quantification of TH positive cells and the density of TH positive fibers (arbitrary unit of intensity), respectively, in SN and STR regions. Values presented are mean ± SD; each group consisted of four mice. Different letters indicate significant differences (p < 0.05) among treatments within mouse stocks (a denotes statistical significance compared to control group, b denotes statistical significance compared to MPTP 10 group, and c denotes statistical significance compared to MPTP 20 group)

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Laboratory Animal Research

ISSN: 2233-7660