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Fig. 2 | Laboratory Animal Research

Fig. 2

From: Verification with the utility of an established rapid assessment of brain safety for newly developed vaccines

Fig. 2

Quantification of mRNA levels of zonula occludens-1 (ZO-1) and occludin in mouse brains. BBB breakdown and restoration were confirmed through expression level analysis of tight junctions in BBB. a ZO-1 mRNA expression after porcine genital respiratory syndrome vaccine (killed-vaccine) injection. b ZO-1 mRNA expression after canine parvovirus vaccine (live-vaccine) injection. c Occludin mRNA expression after porcine genital respiratory syndrome vaccine (killed-vaccine) injection. d Occludin mRNA expression after canine parvovirus vaccine (live-vaccine) injection (*, P < 0.05; **, P < 0.01)

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Laboratory Animal Research

ISSN: 2233-7660