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Table 1 Results for grade of lens opacity according to anaesthetic dose and ocular surface condition in the absence or presence of infrared light exposure in anaesthetised C57BL/6 N mice

From: Evaluation of factors related to Anaesthesia-induced Lens opacity in experimental mice

 

Without infrared light exposure

With infrared light exposure

80% anaesthetic dose

120% anaesthetic dose

80% anaesthetic dose

120% anaesthetic dose

Wet ocular surface

(n = 4)

Dry ocular surface

(n = 4)

Wet ocular surface

(n = 5)

Dry ocular surface

(n = 4)

Wet ocular surface

(n = 3)

Dry ocular surface

(n = 3)

Wet ocular surface

(n = 3)

Dry ocular surface

(n = 3)

10 min after anaesthesia

1.00 ± 0.00

1.00 ± 0.00

1.00 ± 0.00

1.00 ± 0.00

1.00 ± 0.00

1.00 ± 0.00

1.00 ± 0.00

1.00 ± 0.00

15 min after anaesthesia

1.25 ± 0.43

1.25 ± 0.43

1.00 ± 0.00

1.25 ± 0.43

1.00 ± 0.00

1.33 ± 0.47

1.00 ± 0.00

1.00 ± 0.00

20 min after anaesthesia

1.25 ± 0.43

3.25 ± 0.83*

1.00 ± 0.00

3.50 ± 1.12*

1.00 ± 0.00

4.00 ± 0.82*

1.00 ± 0.00

4.66 ± 0.47*

25 min after anaesthesia

1.25 ± 0.43

4.50 ± 0.87*

1.20 ± 0.40

5.25 ± 0.43*

1.00 ± 0.00

6.00 ± 0.00*

1.33 ± 0.47

6.00 ± 0.00*

30 min after anaesthesia

1.25 ± 0.43

5.75 ± 0.43*

1.20 ± 0.40

5.75 ± 0.43*

1.00 ± 0.00

6.00 ± 0.00*

1.33 ± 0.47

6.00 ± 0.00*

  1. Results are expressed as mean ± standard deviation
  2. *p < 0.05 when compared with wet ocular surface in each condition