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Table 1 HBx transgenic mice published

From: Relevance of reactive oxygen species in liver disease observed in transgenic mice expressing the hepatitis B virus X protein

HBV DNA subtypePromoterMouse strainTumor generationPublished paper
adrHBV XCD-1HCCKim et al. (Nature 1991) [28]
adrHBV XF1 hybrid (C57BL/6 X DBA)HCCYu et al. (J of Hepatology 1999) [33]
aywSV40, ATIII, HBV XF1 hybrid (C57BL/6 X DBA)No serious liver damageBILLET et al. (J of Virology 1995) [29]
adwAlpha1 antitrypsinICR females X B6C3F1 males.No tumorLee et al. (J of Virology 1990)
aywHBV XF1 hybrid (C57BL/6 X DBA)No descriptionPerfumo et al. (J of Virology 1992) [31]
No descriptionHBV X, Rat insulin IIC57BL/6, F2 hybrid(C57BL/6 X DBA)No pathological changeReifenberg et al. (J of Hepatology 1997) [32]
aywalbuminC57BL/6HCCWu et al. (BBRC 2006) [34]
No descriptionHBV X in p21 locusC57BL/6HCCWang et al. (Hepatology 2004) [35]