Skip to main content
Fig. 2 | Laboratory Animal Research

Fig. 2

From: Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging

Fig. 2

Microphotographs of Fto immunoreactivity in the hippocampal CA1 region in control (a), high-fat diet-fed obese (b, HFD), and D-galactose-treated aged (c, D-gal) mice. Note that Fto immunoreactivity in all groups is mainly found in the stratum pyramidale (SP), while Fto immunoreactive cells are also abundantly detected in the stratum oriens (SO) and the stratum radiatum (SR) of HFD-fed mice. Scale bar = 50 μm. d Relative optical densities (ROD) are expressed as a percentage of the value of Fto immunoreactivity in the control hippocampal CA1 region per section (n = 5 in each group. The data are analyzed by one-way analysis of variance followed by Bonferroni’s post-hoc test. There are no significant differences in ROD of Fto between groups. The bars indicate the mean values ± standard deviation

Back to article page

Laboratory Animal Research

ISSN: 2233-7660