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Fig. 5 | Laboratory Animal Research

Fig. 5

From: Pathogenicity of severe fever with thrombocytopenia syndrome virus in mice regulated in type I interferon signaling

Fig. 5

Histopathological and immunohistochemical examinations of the spleen collected from the SFTSV-infected mice. Mice were inoculated i.p. with 5 × 102 FAID50 SFTSV. Spleens of the WT and IFNAR Ab mice were collected 1, 3, 7, 12 dpi and the spleens of the IFNAR−/− mice were collected 1 and 3 dpi. a Asterisks indicate white pulp atrophy. Bars, 200 μm. H&E, hematoxylin and eosin staining. b The SFTSV N protein antigens were confirmed in the spleens by immunohistochemistry (IHC). Bars, 100 μm

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