From: Refining drug administration in a murine model of acute infection with Trypanosoma cruzi
Administration method | Number of mice with parasite rebound FBE (%) | Number of mice with quantifiable T. cruzi DNA (%) | Mice with parasitological cure (%) | ||
---|---|---|---|---|---|
Blood | Skeletal muscle | Heart | |||
GAV | 0 / 5 (0%) | 0 / 5 (0%) | 0 / 5 (0%) (4a) | 1 / 5 (20%) (1a) | 5 / 5 (100%) |
TIP | 0 / 5 (0%) | 0 / 5 (0%) | 0 / 5 (0%) (3a) | 0 / 5 (0%) | 5 / 5 (100%) |