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Table 1 Trypanosoma cruzi detection after immunosuppression cycle in a murine model of acute infection

From: Refining drug administration in a murine model of acute infection with Trypanosoma cruzi

Administration method Number of mice with parasite rebound FBE (%) Number of mice with quantifiable T. cruzi DNA (%) Mice with parasitological cure (%)
Blood Skeletal muscle Heart
GAV 0 / 5 (0%) 0 / 5 (0%) 0 / 5 (0%)
(4a)
1 / 5 (20%)
(1a)
5 / 5 (100%)
TIP 0 / 5 (0%) 0 / 5 (0%) 0 / 5 (0%)
(3a)
0 / 5 (0%) 5 / 5 (100%)
  1. FBE fresh blood examination, GAV oral administration method by gavage, TIP oral administration method by pipette and tip
  2. a Number of samples with T. cruzi DNA detectable but below the quantization limit (Ct > 30)