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Table 1 Trypanosoma cruzi detection after immunosuppression cycle in a murine model of acute infection

From: Refining drug administration in a murine model of acute infection with Trypanosoma cruzi

Administration method

Number of mice with parasite rebound FBE (%)

Number of mice with quantifiable T. cruzi DNA (%)

Mice with parasitological cure (%)

Blood

Skeletal muscle

Heart

GAV

0 / 5 (0%)

0 / 5 (0%)

0 / 5 (0%)

(4a)

1 / 5 (20%)

(1a)

5 / 5 (100%)

TIP

0 / 5 (0%)

0 / 5 (0%)

0 / 5 (0%)

(3a)

0 / 5 (0%)

5 / 5 (100%)

  1. FBE fresh blood examination, GAV oral administration method by gavage, TIP oral administration method by pipette and tip
  2. a Number of samples with T. cruzi DNA detectable but below the quantization limit (Ct > 30)