Fig. 2

The muscle fiber size; cross sectional area (CSA). a Representative histological digital images stained by hematoxylin and eosin (HE) of extensor digitorum longus (EDL) muscle, b Comparison of EDL muscle fiber size, c Representative histological digital images stained by HE of soleus (SOL) muscle, d Comparison of EDL muscle fiber size. The reference bar in histological images is equal to 50 μm. The CSA of EDL and SOL muscles in both TS and SHR groups were significantly smaller than that in the control group. Box-and-whisker-plots show 95% confidence interval, 25th percentiles and 75th percentiles, and medians (n = 7 per group). TS, tail suspension, SHR, spontaneously hypertensive rat, *P < 0.05 vs control group