Fig. 3

Difference between the adverse effect of doxorubicin in male- and female-derived xenograft models. a. Mouse’s body weight loss. Body weight of mice was measured during the detection of tumor growth. Data are presented as mean ± standard deviation (n = 4). * p < 0.05 (Student t-test). b. Histology of the left ventricle tissues. Scale bar, 200 μm. c. Histology of the kidney tissues. Scale bar, 100 μm. Tissue sections were stained with hematoxylin and observed under a microscope