Table 1 Effect of Gαq-RGS2 signaling inhibitor on hematological parameters
From: Acute and 28-days subacute toxicity studies of Gαq-RGS2 signaling inhibitor
Parameters | NC | VC | T10 | T100 |
|---|---|---|---|---|
RBC (x106 cells/mm3) | 3.745 ± 0.556 | 3.945 ± 0.556 | 3.712 ± 0.779 | 3.583 ± 0.774 |
Total WBC (x103 cells/mm3) | 6.533 ± 1.244 | 5.833 ± 0.836 | 6.317 ± 1.036 | 6.583 ± 1.049 |
Granulocytes (x103 cells/mm3) | 4.885 ± 1.003 | 5.234 ± 0.668 | 4.693 ± 0.831 | 5.53 ± 0.688 |
Lymphocytes (x103 cells/mm3) | 2.033 ± 0.274 | 2.233 ± 0.287 | 2.417 ± 0.217 | 2.383 ± 0.277 |
Monocytes (x103 cells/mm3) | 0.050 ± 0.012 | 0.057 ± 0.012 | 0.060 ± 0.011 | 0.058 ± 0.012 |
Platelets (x103 cells/µL3) | 265.4 ± 39.30 | 257.4 ± 38.32 | 248.8 ± 29.10 | 257.8 ± 42.12 |
Hb content (g%) | 13.48 ± 1.32 | 13.20 ± 1.07 | 13.92 ± 1.60 | 13.35 ± 0.84 |