Fig. 3

The histopathological structure of CT26 tumor, kidney and liver. a Tumorigenic changes. After harvesting the CT26 tumors from the three BALB/c substrains, the histopathological images were obtained at 400 × magnification, from slide sections of tumor tissue stained with H&E solution. Various tumorigenic changes, such as spindle cells (white arrow), mitotic figures (yellow arrow), vacuolated tumor cells (blue arrow), hemorrhage (red circle), necrosis (green circle) and plumped cell (red arrow), were characterized by a pathologist, Dr. Sang Gu Lee. b Histopathological structure of kidney. Various tumorigenic changes, such as necrosis (white arrow) and tubular bashophilia (yellow arrow), were characterized by a pathologist, Dr. Sang Gu Lee. c Histopathological structure of liver. Five to six mice per group were used for preparation of tissue sections and H&E staining, and histopathological structure was analyzed in duplicate for each tumor