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Fig. 3 | Laboratory Animal Research

Fig. 3

From: Therapeutic effect of intra-articular injected 3′-sialyllactose on a minipig model of rheumatoid arthritis induced by collagen

Fig. 3

Effects of 3′-SL administration on rheumatoid arthritis based on microscopic observation of rheumatoid arthritis induced minipig model. A Representative cell cloning images obtained by H&E and Safranin-O staining of the articular cartilage of the knee joint. Black arrow indicates cell cloning. 100 × magnification, Scale bar = 200 µm. B Quantification results of chondrocyte density, cell cloning, and surface irregularities via macroscopic observations based on OARIS scores. Error bars represent SD. *, p < 0.05; **, p < 0.01, One-way analysis of variance. VC: vehicle control; G1: 2 mg/kg treatment group; G2: 10 mg/kg treatment group; G3: 50 mg/kg treatment group

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Laboratory Animal Research

ISSN: 2233-7660