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Fig. 4 | Laboratory Animal Research

Fig. 4

From: Therapeutic effect of intra-articular injected 3′-sialyllactose on a minipig model of rheumatoid arthritis induced by collagen

Fig. 4

Effects of 3′-SL administration on rheumatoid arthritis related pathogenic pathway in the synovial membrane of a minipig model of RA. AC Relative expression levels of IL-1β, TNFα, and COX2 in the synovial membrane of rheumatoid arthritis induced knee joints by qRT-PCR. Error bars represent SD. *, p < 0.05; ****, p < 0.001, One-way analysis of variance. VC: vehicle control; G1: 2 mg/kg treatment group; G2: 10 mg/kg treatment group; G3: 50 mg/kg treatment group

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