Fig. 1

Effects of resistance exercise training on the skeletal muscle mass and function in mice. A Experimental scheme of resistance exercise training and HFD. B Mice resistance climbing exercise protocol. C Skeletal muscle weight (g) to body weight (g) ratio upon sacrifice, n = 4 for each group. D Fore-limb grip strength was measured, SED-HF; n = 6, REX-HF; n = 9. E The length of time until the mice fell from the hanging wire was recorded, n = 8 for all group. F qPCR analysis of myogenin gene expression in skeletal muscles, n = 4. Values are presented as mean ± SEM. Significant differences were determined using an unpaired two-tailed Student’s t-test. *p < 0.05