Table 2 Alteration on the blood analysis parameters of Rag2/Korl and Rag2/J KO mice
From: Comparison of immunophenotypes between Rag2 knockout mice derived from two different sources
Category | C57BL/6-Rag2em1hwl/Korl | B6.Cg-Rag2tm1.1Cgn/J | ||||
|---|---|---|---|---|---|---|
WT | KO | Change ratio (%) | WT | KO | Change ratio (%) | |
WBC (× 103 cells/μL) | 4.01 ± 0.29 | 1.70 ± 0.26* | −58.62 ± 6.58 | 4.92 ± 1.56 | 0.73 ± 0.15* | −84.58 ± 3.65# |
LYM (× 103 cells/μL) | 3.39 ± 0.17 | 0.26 ± 0.06* | −93.04 ± 1.84 | 4.30 ± 1.19 | 0.15 ± 0.02* | −96.26 ± 1.68# |
NEU (× 103 cells/μL) | 0.37 ± 0.11 | 1.38 ± 0.20* |  + 280.28 ± 146.16 | 0.20 ± 0.06 | 0.56 ± 0.07* |  + 262.46 ± 43.67 |
RBC (× 106 cells/μL) | 9.29 ± 0.82 | 8.74 ± 0.25 | −5.94 ± 11.05 | 9.25 ± 0.41 | 8.78 ± 0.43 | −5.02 ± 5.32 |
HGB (g/dL) | 12.33 ± 0.33 | 11.1 ± 0.34* | −9.10 ± 0.73 | 12.48 ± 0.33 | 11.53 ± 0.25* | −5.58 ± 4.33 |
HCT (%) | 39.93 ± 0.98 | 36.42 ± 0.76* | −8.41 ± 0.42 | 40.01 ± 1.52 | 37.65 ± 1.33 | −4.74 ± 5.22 |
MCV (fL) | 40.50 ± 0.58 | 40.80 ± 0.84 |  + 0.83 ± 2.83 | 42.0 | 42.2 ± 0.45 |  + 0.48 ± 1.06 |
MCH (pg) | 12.88 ± 0.37 | 12.55 ± 0.39 | −2.28 ± 4.65 | 13.08 ± 0.36 | 13.13 ± 0.35 | −0.38 ± 6.85 |
MCHC (g/dL) | 30.94 ± 1.63 | 30.73 ± 1.89 | −0.43 ± 8.41 | 31.03 ± 0.95 | 31.03 ± 0.88 | −0.50 ± 7.20 |
RDW (%) | 17.82 ± 0.42 | 17.25 ± 0.46 | −3.03 ± 1.57 | 17.28 ± 0.27 | 17.98 ± 0.54 |  + 4.09 ± 4.30# |
PLT (× 103 cells/μL) | 490.67 ± 38.08 | 654.25 ± 4.27* |  + 27.72 ± 2.00 | 489.67 ± 17.90 | 432.3 ± 4.51* | −17.56 ± 10.26# |
MPV (fL) | 6.13 ± 0.06 | 5.95 ± 0.10 | −1.64 ± 2.32 | 5.86 ± 0.06 | 5.77 ± 0.15 | −1.36 ± 2.81 |