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Fig. 2 | Laboratory Animal Research

Fig. 2

From: SARS-CoV-2 Omicron variant causes brain infection with lymphoid depletion in a mouse COVID-19 model

Fig. 2

Comparison of viral infection in the lungs and brains of Wuhan- and Omicron-infected K18-hACE2 mice. A IHC images for SARS-CoV-2 N protein in the lungs and brains of Wuhan-infected K18-hACE2 mice at 7 dpi. Scale bar = 500 μm (low power) and 100 μm (high power). The body weight and temperature of each mouse are provided below the IHC images. B IHC images of SARS-CoV-2 N protein in the lungs and brains of Omicron-infected K18-hACE2 mice at 7 dpi. Scale bar = 500 μm (low power) and 100 μm (high power). The body weight and temperature of each mouse are provided below the IHC images. C Representative ISH images of viral spike protein mRNA (S gene, Red) in the brain of Omicron-infected mouse #5. Scale bar = 200 μm (low power) and 50 μm (high power). The boxed areas are magnified in the right panels

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