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  1. Cynomolgus monkeys as nonhuman primates are valuable animal models because they have a high level of human gene homology. There are many reference values for hematology and biochemistry of Cynomolgus monkeys t...

    Authors: Kangmoo Choi, Jaejin Chang, Min-Jae Lee, Seungsu Wang, Kimhong In, Wilhelm C. Galano-tan, Sanghun Jun, Kahee Cho, Yong-Hwa Hwang, Sung-Ju Kim and Wanje Park
    Citation: Laboratory Animal Research 2016 32:6
  2. Asparagus cochinchinensis has been used to treat various diseases including fever, cough, kidney disease, breast cancer, inflammatory disease and brain disease, while IL-4 cytokine has been considered as key regu...

    Authors: Ji-Eun Sung, Hyun-Ah Lee, Ji-Eun Kim, Jun Go, Eun-Ji Seo, Woo-Bin Yun, Dong-Seob Kim, Hong-Joo Son, Chung-Yeoul Lee, Hee-Seob Lee and Dae-Youn Hwang
    Citation: Laboratory Animal Research 2016 32:5
  3. In this study, the potential hepatotoxicity of 1,3-dichloro-2-propanol and its hepatotoxic mechanisms in rats was investigated. The test chemical was administered orally to male rats at 0, 27.5, 55, and 110 mg...

    Authors: In-Chul Lee, Sang-Min Lee, Je-Won Ko, Sung-Hyeuk Park, In-Sik Shin, Changjong Moon, Sung-Ho Kim and Jong-Choon Kim
    Citation: Laboratory Animal Research 2016 32:4
  4. As the request of the authors, the following information has been changed.

    Authors: Jangbeen Kyung, Dajeong Kim, Dongsun Park, Yun-Hui Yang, Ehn-Kyoung Choi, Sung-Pyo Lee, Tae-Su Kim, Yoon-Bok Lee and Yun-Bae Kim
    Citation: Laboratory Animal Research 2015 31:3103153

    The original article that this is related to.

  5. In order to assess inhibitory potentials of white rose petal extracts (WRPE) on the activities of enzymes related to dermal aging according to the extraction conditions, three extraction methods were adopted. ...

    Authors: Ehn-Kyoung Choi, Haiyu Guo, Jae-Kwon Choi, Su-Kil Jang, Kyungha Shin, Ye-Seul Cha, Youngjin Choi, Da-Woom Seo, Yoon-Bok Lee, Seong-Soo Joo and Yun-Bae Kim
    Citation: Laboratory Animal Research 2015 31:3103148
  6. The aim of this study was to verify subacute oral dose toxicity of positively charged 100 nm zinc oxide (ZnOAE100[+]) nanoparticles (NPs) in Sprague-Dawley rats. ZnOAE100[+] NPs were administered to rats of each ...

    Authors: Je-Won Ko, Eun-Taek Hong, In-Chul Lee, Sung-Hyeuk Park, Jong-Il Park, Nak-Won Seong, Jeong-Sup Hong, Hyo-In Yun and Jong-Choon Kim
    Citation: Laboratory Animal Research 2015 31:3103139
  7. Curcumin provides various biological effects through its anti-inflammatory and antioxidant properties. Moreover, curcumin exerts a neuroprotective effect against ischemic condition-induced brain damage. Protei...

    Authors: Fawad-Ali Shah, Dong-Ju Park, Sang-Ah Gim and Phil-Ok Koh
    Citation: Laboratory Animal Research 2015 31:3103134
  8. Some polymers and bioactive compounds derived from Styela clava tunic (SCT) have been reported as traditional medicine for the treatment of inflammation, oxidative stress and surgical wounds although there is lit...

    Authors: Eun-Kyoung Koh, Ji-Eun Sung, Ji-Eun Kim, Jun Go, Sung-Hwa Song, Hyun-Ah Lee, Hong-Joo Son, Young-Jin Jung, Yong Lim and Dae-Youn Hwang
    Citation: Laboratory Animal Research 2015 31:3103125
  9. This study was conducted to investigate the effects of lutein alone or in combination with vitamin C on the antioxidant defense system in rats. A total of 18 eight-week-old male Sprague Dawley (SD) rats were r...

    Authors: Min-Hae Song, Eu-Chul Shin, Dae-Youn Hwang and In-Surk Jang
    Citation: Laboratory Animal Research 2015 31:3103117
  10. The effect of pentoxifylline (PTX) administration on histomorphological parameters of streptozotocin (STZ)-induced type 1 diabetes mellitus (DM) in male rat testes were evaluated. We randomly divided 40 male r...

    Authors: Abbas Piryaei, Azam Najar and Mohammad Bayat
    Citation: Laboratory Animal Research 2015 31:3103111
  11. To evaluate the hepatotoxicity and nephrotoxicity of Galla Rhois (GR) toward the liver and kidney of ICR mice, alterations in related markers including body weight, organ weight, urine composition, liver patho...

    Authors: Jun Go, Ji-Eun Kim, Eun-Kyoung Koh, Sung-Hwa Song, Ji-Eun Seung, Chan-Kyu Park, Hyun-Ah Lee, Hong-Sung Kim, Jae-Ho Lee, Beum-Soo An, Seung-Yun Yang, Yong Lim and Dae-Youn Hwang
    Citation: Laboratory Animal Research 2015 31:3103101
  12. As the request of the authors, the following information has been changed.

    Authors: Jingmei Cai, Tae-Su Kim, Ja Young Jang, Jihyun Kim, Kyungha Shin, Sung-Pyo Lee, Ehn-Kyoung Choi, Sa-Hyun Kim, Min Park, Jong Bae Kim and Yun-Bae Kim
    Citation: Laboratory Animal Research 2015 31:3102099

    The original article that this is related to.

  13. We developed pancreatic and duodenal homeobox1 (Pdx1) knockout mice to improve a compensatory hyperinsulinemia, which was induced by hyperplasia in the β cells or Langerhans’ islands, as the diabetic model mice. ...

    Authors: Haruo Hashimoto, Tsutomu Kamisako, Takahiro Kagawa, Seiki Haraguchi, Mika Yagoto, Ri-ichi Takahashi, Kenji Kawai and Hiroshi Suemizu
    Citation: Laboratory Animal Research 2015 31:3102093
  14. A number of Helicobacter species may confound experimental data because of their association with disease progressing in various kinds of laboratory animals. Screening of Helicobacter species is particularly desi...

    Authors: Sunhwa Hong, Yungho Chung, Won-Guk Kang, Yeon-Shik Choi and Okjin Kim
    Citation: Laboratory Animal Research 2015 31:3102086
  15. Streptococcus pneumoniae is a major human pathogen that is involved in community-acquired pneumonia. Tumor necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine that activates immune responses against infe...

    Authors: Dong-Gu Jeong, Jin-Hee Seo, Seung-Ho Heo, Yang-Kyu Choi and Eui-Suk Jeong
    Citation: Laboratory Animal Research 2015 31:3102078
  16. Gastrodia elata (GE) is traditionally used for treatment of various disorders including neurodegenerative diseases such as Alzheimer’s disease. To investigate the neuroprotective effect of GE, amyloid-β peptide (...

    Authors: Young-Mi Park, Bong-Gun Lee, Sang-Hoon Park, Hong-Geun Oh, Yang-Gyu Kang, Ok-Jin Kim, Lee-Seong Kwon, Yong-Phill Kim, Min-Hyu Choi, Yong-Seob Jeong, Jisun Oh and Hak-Yong Lee
    Citation: Laboratory Animal Research 2015 31:3102069
  17. Coronary artery disease is a common occurrence in human, and causes enormous social cost. Poncirus fructus (PF), the dried immature fruits of Poncirus trifoliata Rafinesquem, is used in the treatment of womb cont...

    Authors: Dong-Jun Yu, Jin-Hong Jun, Tae-Jun Kim, Dong-Kyun Suh, Dong-ho Youn and Tae-Wan Kim
    Citation: Laboratory Animal Research 2015 31:3101033
  18. Since scalp hair loss has increased recently even in young people, seriously affecting individual’s quality of life, the hair growth-stimulating effects of Laminaria japonica extract (LJE) and Cistanche tubulosa ...

    Authors: Kyungha Shin, Tae-Su Kim, Jangbeen Kyung, Dajeong Kim, Dongsun Park, Ehn-Kyoung Choi, Sung-Pyo Lee, Woong-Suk Yang, Myung-Hwa Kang and Yun-Bae Kim
    Citation: Laboratory Animal Research 2015 31:3101024
  19. Some biological effects of Red Liriope platyphylla (RLP) on various chronic diseases including Alzheimer’s disease, diabetes and obesity were suggested after a report of the production from Liriope platyphylla (L...

    Authors: Young-Ju Lee, Eun-Kyoung Koh, Ji-Eun Kim, Jun Go, Sung-Hwa Song, Ji-Eun Seong, Hong-Joo Son, Byeong-Cheol Kang and Dae-Youn Hwang
    Citation: Laboratory Animal Research 2015 31:3101013
  20. Helicobacter pylori-eliminating effects of FEMY-R7, composed of Laminaria japonica and Oenothera biennis extracts, were investigated in mice and humans. Male C57BL/6 mice were infected with the bacteria by intrag...

    Authors: Tae-Su Kim, Kyungha Shin, Joseph H. Jeon, Ehn-Kyoung Choi, Youngjin Choi, Sung-Pyo Lee, Yoon-Bok Lee and Yun-Bae Kim
    Citation: Laboratory Animal Research 2015 31:3101007
  21. The leptin receptor-deficient db/db mouse is a rodent model of type 2 diabetes and obesity. Diabetes in db/db mice shows an age-dependent progression, with early insulin resistance followed by an insulin secretor...

    Authors: Hye-Min Choi, Hae Rim Kim, Eun-Kyoung Kim, Yong Sub Byun, Young-Suk Won, Won-Ki Yoon, Hyoung-Chin Kim, Jong-Goo Kang and Ki-Hoan Nam
    Citation: Laboratory Animal Research 2015 31:3101001
  22. Eosinophilic, polymorphic and pruritic eruption associated with radiotherapy (EPPER) can occur in cancer patients after irradiation. In this study, we characterized the clinical and histopathological features ...

    Authors: Joong Sun Kim, Won Seok Jang, Min Ji Bae, Sunhoo Park and Seung Sook Lee
    Citation: Laboratory Animal Research 2015 31:7
  23. Curcumin exerts a protective effect in cerebral ischemia through its anti-oxidant and anti-inflammatory activities. γ-enolase is a glycolytic enzyme expressed in neurons that is known to exerts a neuroprotecti...

    Authors: Sang-Ah Gim, So-Ra Lee, Fawad-Ali Shah and Phil-Ok Koh
    Citation: Laboratory Animal Research 2015 31:6
  24. Inflammation has recently been implicated in cancer formation and progression. As tissue transglutaminase (TG2) has been associated with both inflammatory signaling and tumor cell behavior, we propose that TG2...

    Authors: Keunhee Oh, Hyeong-Gon Moon, Dong-Sup Lee and Young-Bok Yoo
    Citation: Laboratory Animal Research 2015 31:5
  25. The aim of this study is to assess the effects of different glucocorticoid administration protocols on biomechanical properties of the first lumbar vertebral body in rats. We divided 40 male rats into the foll...

    Authors: Azam Najar, Mohammadjavad Fridoni, Fatemesadat Rezaei, Saba Bayat and Mohammad Bayat
    Citation: Laboratory Animal Research 2015 31:4
  26. Procedures involving complex surgical techniques in rats, such as placement of abdominal aortic graft require extended duration of surgical anesthesia, which often can be achieved by repeated administrations o...

    Authors: Arun H. S. Kumar and Anthony J. P. Clover
    Citation: Laboratory Animal Research 2015 31:3
  27. Genetic background in animal models is an intrinsic research variable in biomedical research. Although inbred strains offer genetic uniformity, the outbred stocks, known for genetic variability are often used ...

    Authors: Marcia Brower, Martha Grace, Catherine M. Kotz and Vijay Koya
    Citation: Laboratory Animal Research 2015 31:2
  28. The common marmoset (Callithrix jacchus) is a small-bodied, popular New World monkey and is used widely in reproductive biology, neuroscience, and drug development, due to its comparative ease of handling, high r...

    Authors: Jun-Won Yun, Jae-Bum Ahn and Byeong-Cheol Kang
    Citation: Laboratory Animal Research 2015 31:1

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  • Laboratory Animal Research is the official journal of the Korean Association for Laboratory Animal Science. KALAS was established in 1985 in order to discuss the knowledge of the experiment, and promote the science and technology in laboratory animal sciences.

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