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Table 4 Biochemical parameter values of cynomolgus monkeys aged 48–96 months

From: Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride

Parameter (unit)

Males

(n = 28)

Females

(n = 114)

Male range

(n = 28)

Female range

(n = 114)

AST (U/l)

33.6 ± 24.5

31.9 ± 15.3

15.0–114

13.0–106

ALT (U/l)

8.70 ± 6.92

11.8 ± 10.9

1.00–29.0

1.00–56.0

ALP (U/l)

667 ± 337

376 ± 133***

188–1670

158–741

BUN (mg/dl)

18.6 ± 5.37

16.1 ± 4.23*

7.20–30.7

7.50–28.0

CRE (mg/dl)

0.94 ± 0.27

0.71 ± 0.20***

0.60–1.60

0.10–1.10

GLU (mg/dl)

67.5 ± 18.5

67.4 ± 16.4

33.0–120

26.0–130

TCHO (mg/dl)

105 ± 27.8

123 ± 31.4*

52.0–164

37.0–203

ALB (g/dl)

3.87 ± 0.49

3.85 ± 0.38

2.90–4.90

2.20–4.80

TP (g/dl)

6.68 ± 0.66

6.72 ± 0.60

5.40–7.60

4.60–8.10

TG (mg/dl)

42.4 ± 37.6

46.4 ± 28.0

8.00–215

9.00–213

TBIL (mg/dl)

0.27 ± 0.18

0.34 ± 0.26

0.10–0.08

0.10–2.30

IP (mg/dl)

4.35 ± 1.14

3.74 ± 1.10*

1.20–6.90

1.10–6.60

Ca (mg/dl)

8.30 ± 0.82

8.44 ± 0.67

6.80–9.90

6.20–9.90

GGT (U/l)

83.4 ± 33.1

63.7 ± 26.2**

35.0–181

1.00–199

LDH (U/l)

268 ± 198.8

194 ± 100.7**

53.0–900

31.0–467

DBIL (mg/dl)

0.13 ± 0.06

0.19 ± 0.12*

0.10–0.30

0.10–0.80