Table 1 Comparison of age, sex distribution, and doses of anesthetics between young and aged mice (left column) and between surviving and deceased aged mice (right column)
From: Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine
young (n = 26) | aged (n = 26) | p | surviving aged (n = 22) | deceased aged (n = 4) | p | |
|---|---|---|---|---|---|---|
age in months (mean ± SD) | 2.14 ± 0.23 | 26.31 ± 2.15 | < 0.0001 | 26.18 ± 2.26 | 27.0 ± 1.35 | 0.49 |
sex distribution [female: n (%)] | 17 (65%) | 18 (69%) | 0.77 | 15 (68%) | 3 (75%) | 0.79 |
weight in g (mean ± SD) | 23.2 ± 3.4 | 32.8 ± 5.4 | < 0.0001 | 33.3 ± 5.0 | 30.2 ± 7.5 | 0.30 |
ketamine dose (mg/kg) | 87.9 ± 12.0 | 62.6 ± 10.3 | < 0.0001 | 61.4 ± 9.0 | 69.3 ± 16.0 | 0.17 |
xylazine dose (mg/kg) | 8.8 ± 1.2 | 6.3 ± 1.0 | < 0.0001 | 6.2 ± 0.9 | 6.9 ± 1.6 | 0.17 |