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Fig. 1 | Laboratory Animal Research

Fig. 1

From: Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources

Fig. 1

Comparative analysis of physiological responses to acute MPTP administration (four injections at two-hour intervals) among different stocks of C57BL/6 mice. a-c Dose-dependent changes in body weight and (d-f) temperature (hypothermic response) over an eight hour period. g Distribution and dose-dependent changes in mouse body composition (total mass, lean mass, and fat tissue). Values are presented as mean ± SD; each group consisted of 6–15 mice. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to control group

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Laboratory Animal Research

ISSN: 2233-7660