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Fig. 3 | Laboratory Animal Research

Fig. 3

From: Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources

Fig. 3

Comparative analysis of the nigrostriatal neurotoxicity and protein oxidation from acute MPTP administration among C57BL/6 mice stocks. a and d Representative western blots showing levels of tyrosine hydroxylase (TH) expression and protein carbonylation, respectively. b, c, e, and f Densitometric analyses of blots normalized for density of Ponseau staining in the SN and STR tissues of different C57BL/6 stocks. The dashed line indicates the level of the control group. Values presented are mean ± SD; each group consisted of six mice. Different letters indicate a significant difference (p < 0.05) among treatment groups within mouse stocks (a denotes statistical significance compared to control group, b denotes statistical significance compared to MPTP 10 group, and c denotes statistical significance compared to MPTP 20 group)

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Laboratory Animal Research

ISSN: 2233-7660