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Fig. 3 | Laboratory Animal Research

Fig. 3

From: Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus

Fig. 3

Immunohistochemistry for Ki67 in the dentate gyrus of control (a), vehicle- (b), control-HSP70- (c), and Tat-HSP70-treated (d) mice. In all groups, Ki67-positive nuclei (arrows) are found in the subgranular zone of the dentate gyrus. Note that Ki67-positive nuclei are abundantly detected in the dentate gyrus of control-HSP70 and Tat-HSP70-treated mice. GCL, granule cell layer; ML, molecular layer; PL, polymorphic layer. Scale bar = 50 μm. e The number of Ki67-positive nuclei in the dentate gyrus per section for each group are also shown (n = 5 per group; aP < 0.05, versus control group; bP < 0.05, versus vehicle-treated group). Data are presented as mean ± SEM

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