Table 1 Hematological analysis data of STX-0119 treated mice
From: Inhibition of STAT3 signaling induces apoptosis and suppresses growth of lung cancer: good and bad
Parameter | Control (n=8) | STX-0119 (80mg/kg, n=7) | STX-0119 (160mg/kg, n=7) | ||
|---|---|---|---|---|---|
Mean±SD | Mean±SD | p-value(T-test) | Mean±SD | p-value(T-test) | |
WBC(X10³ cell/μl) | 5.59±2.25 | 4.58±2.5 | 0.444 | 2.49±.87 | 0.005 |
RBC(X106 cell/μl) | 8.29±.82 | 8.37±.60 | 0.839 | 8.32±.48 | 0.929 |
HGB(g/dl) | 13.51±.69 | 13.17±.91 | 0.444 | 13.01±.68 | 0.199 |
HCT(%) (37-55) | 45.00±3.40 | 44.83±3.48 | 0.927 | 42.94±1.53 | 0.170 |
MCV(fL) | 54.47±2.57 | 53.6±1.89 | 0.484 | 51.7±1.34 | 0.026 |
MCH(pg) | 16.41±1.17 | 15.77±.63 | 0.224 | 15.66±.57 | 0.149 |
MCHC(g/dl) | 30.13±1.59 | 29.41±.48 | 0.277 | 30.33±1.05 | 0.786 |
RDW(%) | 14.11±2.73 | 13.04±1.06 | 0.352 | 13.27±.95 | 0.456 |
PLT(X10³ cell/μl) | 1014.86±239.79 | 1273.86±191.19 | 0.045 | 1116.29±201.41 | 0.408 |
MPV(fL) | 5.79±0.34 | 5.94±0.28 | 0.368 | 6.19±0.72 | 0.207 |
NEUT(%) | 26.27±6.18 | 30.96±6.87 | 0.205 | 29.26±5.23 | 0.349 |
LYM(%) | 65.26±5.65 | 62.17±6.09 | 0.345 | 63.27±4.42 | 0.478 |
MONO(%) | 0.8±0.24 | 1.03±0.43 | 0.243 | 0.8±0.38 | 1.000 |
EOS(%) | 1.46±0.42 | 1.87±1.09 | 0.366 | 2.37±0.63 | 0.008 |
LUC(%) | 6.11±5.58 | 3.86±2.68 | 0.354 | 4.16±5.77 | 0.531 |
BASO(%) | 0.07±0.08 | 0.11±0.09 | 0.354 | 0.11±0.11 | 0.403 |