Nonhuman primate model in mammary gland biology and neoplasia research

Table 1 Nonhuman primate models in breast development and neoplasia research

Type of Model	Reported Species	References
Breast Cancer Studies
Spontaneous mammary neoplasia	Macaca mulatta	[50, 52,53,54]
	Macaca fascicularis
	Papio sp.
	Chlorocebus aethiops
Chemically-induced mammary neoplasia	Macaca mulatta	[55]
	Macaca fascicularis
	Chlorocebus aethiops
Breast Developmental and/or Cancer Risk Studies
HRT or SERM exposure	Macaca fascicularis	[36, 46,47,48,49, 56,57,58,59]
Dietary exposure	Macaca fascicularis	[33, 34, 48, 49, 60]
EDC	Macaca mulatta	[61]
Other Applications
Breast profiling at specific developmental stages to model carcinogenesis	Macaca fascicularis	[28, 33,34,35, 41]
	Macaca mulatta	[28, 33,34,35, 41]
Ex vivo mammary culture model	Macaca mulatta	[51, 62, 63]
	Macaca fascicularis
	Papio hamadryas anubis
	Callithrix jacchus

HRT Hormone replacement therapy, SERM Selective estrogen receptor modulator, EDC Endocrine disrupting chemicals

ISSN: 2233-7660