Table 2 Gene ontology and KEGG pathways related to human ACE2 overexpression in hearts of dTg mice
P-value | KEGG pathway | Gene counts |
|---|---|---|
3.70E-04 | ECM-receptor interaction | 8 |
5.55E-04 | Metabolism of xenobiotics by cytochrome P450 | 7 |
0.00359981 | Arachidonic acid metabolism | 6 |
0.01443938 | Type II diabetes mellitus | 4 |
0.02960078 | Cytokine-cytokine receptor interaction | 31 |
0.030258432 | TGF-beta signaling pathway | 5 |
0.03164412 | Glycolysis / Gluconeogenesis | 4 |
0.033455342 | Starch and sucrose metabolism | 4 |
0.049109556 | One carbon pool by folate | 2 |
0.002257311 | Apoptosis | 10 |
0.013300485 | Nitrogen metabolism | 4 |
0.016855394 | Calcium signaling pathway | 14 |
0.0169800262 | Fatty acid biosynthesis | 2 |
0.023873353 | Hematopoietic cell lineage | 8 |
0.03435755 | Amyotrophic lateral sclerosis (ALS) | 3 |