Fig. 3
From: Early high-fat feeding improves histone modifications of skeletal muscle at middle-age in mice
Effects of high-fat diet feeding on gene expressions in the tibialis anterior muscle. Gene expressions were measured in Control (gray) and High-fat (blue) groups at 3-mo-old (n = 6 in each group, a) and 13-mo-old (n = 12 in each group, b). All values of each gene obtained from qPCR were normalized with that of Gapdh mRNA, followed by the values were expressed to the mean of respective control level was 1. Values are shown as mean ± SEM. *: p < 0.05 vs. age-matched control group examined by unpaired t-test. Nox2, NADPH oxidase 2; Pdk4, pyruvate dehydrogenase kinase 4; Ppargc1a, peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Ucp3, mitochondrial uncoupling protein 3; Zmynd17, zinc finger MYND domain-containing protein 17; Glut4, glucose transporter type 4; Irs1, insulin receptor substrate 1