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Fig. 2 | Laboratory Animal Research

Fig. 2

From: High fat diet accelerates and exacerbates microgliosis and neuronal damage/death in the somatosensory cortex after transient forebrain ischemia in gerbils

Fig. 2

Iba-1 immunohistochemistry in the somatosensory cortex of the ND/sham (A), ND/TFI (B-D), HFD/sham (E), and HFD/TFI (F-H) groups at 1 day, 2 days, and 5 days after TFI. Microgliosis (hypertrophied Iba-1 immunoreactive cells and increased Iba-1 immunoreactivity) in the ND/TFI group is apparent at 5 days after TFI, however, microgliosis in the HFD/TFI group begins from 1 day after TFI and aggravates with time. Scale bar = 200 μm (A–H), 30 μm (a–p). I ROD of Iba-1 immunoreactive microglia in layer III and V (n = 5 in each sham group, n = 7 in each TFI group; ∗P < 0.05 vs. each sham group, †P < 0.05 vs. pre-time point group, and #P < 0.05 vs. ND/TFI group). The bars indicate the means ± SEM

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Laboratory Animal Research

ISSN: 2233-7660