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Fig. 5 | Laboratory Animal Research

Fig. 5

From: Comparative analysis of restraint stress-induced depressive-like phenotypes in C57BL/6N mice derived from three different sources

Fig. 5

Effect of repeated RST treatment on histological expression pattern of TPH-positive neurons in raphe nuclei. Representative histological images and quantification of TPH-positive cells in (a) the dorsal raphe nucleus (DRN) and (b) the median raphe nucleus (MRN), and (c) the medullary raphe nucleus (10x magnification). TPH-positive cells were identified as brown granular dots. Results are expressed as TPH+ cell number per section. Scale bar = 250 μm. Data are presented as the mean ± SEM; n = 4 mice per group. RST, restraint stress; TPH, tryptophan hydroxylase; SEM, mean ± standard error

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Laboratory Animal Research

ISSN: 2233-7660