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Fig. 2 | Laboratory Animal Research

Fig. 2

From: Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats

Fig. 2

Skin score of irradiation dose selection test using 8-MOP in SD rats. a Dose-dependent skin reaction after 24 h of UVA 5, 10, 15, 20 J/cm2 administered with 8-MOP 0.01, 0.001, 0.0001 w/v %. b Time-dependent skin reaction after 24, 48, 72 h of UVA 10, 15 J/cm2 administered with 8-MOP 0.01 w/v %. Data of non-irradiated group are not shown because no have scores. Mean score = Total of erythema and edema scores/Number of animals tested (n = 3)

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