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Table 2 Skin scores of SD rats after 48 h of UVA and UVB irradiation

From: Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats

Group

Test substance

Concentration

(w/v %)

Mean score

erythema

edema

UV(+)

8-MOP

0.01

2.3

1.3

IBF

25

1.6

0.3

BPO

10

0.6

0

KPF

80

1.3

0

PXC

2

1.6

0

SBZ

1

0

0

UV(−)

8-MOP

0.01

0

0

IBF

25

0

0

BPO

10

0

0

KPF

80

0

0

PXC

2

0

0

SBZ

1

0

0

  1. There were three SD rats per group. No phototoxic response (erythema, edema) was observed in the non-irradiation site at all time