Fig. 3
From: Extensive variability in the composition of immune infiltrate in different mouse models of cancer
T cells are the dominant lymphocytes in IC CT26 tumours while B cells are the dominant lymphocyte in SC CT26 tumours. a Endpoint weight of tumours injected intracaecally (IC) or subcutaneously (SC). If multiple tumours grew, these were combined and weighed together. Each data point represents tumour weight from an individual mouse. Data are shown with median. b Frequencies of lymphocyte populations in intracaecal (top graph) and subcutaneous (bottom graph) CT26 tumours. c Frequencies of lymphocyte populations in the spleens of mice injected IC (top graph) or SC (bottom graph) with CT26 tumours. Frequencies were normalised to 100. Each bar represents an individual mouse. IC tumours and spleens 1–4 were collected and analysed separately. All other tumours were collected and analysed in batches, as indicated by the blue bars. d Pooled data from all mice in all experiments shown in B and C; median +/− SD. IC n = 12, from 7 individual experiments. SC n = 25, from 4 individual experiments