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Fig. 5 | Laboratory Animal Research

Fig. 5

From: Extensive variability in the composition of immune infiltrate in different mouse models of cancer

Fig. 5

Myeloid cells are CD11b+ CD11c+ and F4/80+ in both IC and SC tumours but there is heterogeneity in spleen cell frequencies. a Frequency of myeloid cell populations in in intracaecal (top graph) and subcutaneous (bottom graph) CT26 tumours. Frequencies were normalised to 100. Each bar represents an individual mouse. b Frequencies of myeloid cell populations in the spleens of mice challenged IC (top graph) or SC (bottom graph) with CT26 tumours. Frequencies were normalised to 100. Each bar represents an individual mouse. IC tumours and spleens 1–4 were collected and analysed separately. All other tumours were collected and analysed in batches, as indicated by the blue bars. c Pooled data from all mice in all experiments shown in a and b; median +/− SD. IC n = 12, from 7 individual experiments. SC n = 25, from 4 individual experiments

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