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Fig. 1 | Laboratory Animal Research

Fig. 1

From: Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice

Fig. 1

Effect of Wdr13 deletion on liver regeneration after CCl4 administration a Ki-67 immunostaining of liver sections from control and CCl4 administered Wdr13+/0 and Wdr13−/0 mice. b Quantitative representation of Ki-67 positive cells from control and CCl4 administered Wdr13+/0 and Wdr13−/0 liver. c Liver/body weight ratios of control and CCl4 administered Wdr13+/0 and Wdr13−/0 mice. d p53, Cyclin E and Cyclin D1 immunoblots performed on liver proteins. All the images presented here are cropped images of full length blots for better representation and all the gels were run under similar experimental conditions. e Relative protein levels of p53, Cyclin E and Cyclin D1 showed in (d) immunoblots. ImageJ analysis of western blots was performed for quantification normalised with respective β-actin as loading control. n = 5 mice for controls and n = 8 mice for treatment group, **p < 0.01, ***p < 0.001

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