Fig. 3
From: Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice
Effect of Wdr13 deletion on liver PPAR pathway after CCl4 administration a AC1, P-p38α, p38α and PPARγ immunoblots performed on liver proteins. All the images presented here are cropped images of full length blots for better representation and all the gels were run under similar experimental conditions. b Relative protein levels of AC1, p38α and PPARγ showed in (a) immunoblots. ImageJ analysis of western blots was performed for quantification normalised with respective β-actin as loading control. c Relative mRNA expression levels of PPAR pathway genes in CCl4 treated Wdr13+/0 and Wdr13−/0 mice. d Relative mRNA expression levels of PPARγ target genes in CCl4 treated Wdr13+/0 and Wdr13−/0 mice. n = 5 mice for controls and n = 8 mice for treatment group, *p < 0.05, **p < 0.01. (AC1- Adenylyl Cyclase 1)