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Fig. 3 | Laboratory Animal Research

Fig. 3

From: Comparison of intrinsic exercise capacity and response to acute exercise in ICR (Institute of Cancer Research) mice derived from three different lineages

Fig. 3

Comparative analysis of the cardiac mitochondrial oxidative phosphorylation (OXPHOS) complex, mitochondrial function, and uncoupling protein (UCP) 3 expression levels among the ICR lineages. A Representative western blots showing the protein levels of the OXPHOS complex. B The densitometric analysis of blots normalized for COX-IV in the cardiac mitochondrial fraction of different ICR lineages. C Oxygen consumption rate (OCR) in the permeabilized cardiac muscles of different ICR lineages was recorded using the Oroboros O2K instrument. D The respiratory control ratio (RCR) was calculated as the ratio of oxygen consumption at state 3 (complex 1 and complex 1 + 2) to that at state 2. E Representative western blots showing the protein levels of UCP3 in the soleus, extensor digitorum longus (EDL), and cardiac muscle. F The densitometric analysis of blots normalized for the density of Ponceau staining in different muscles. The values are presented as mean ± SEM; each group consisted of 5–6 mice. *P < .05, **P < .01, and ***P < .001

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Laboratory Animal Research

ISSN: 2233-7660