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Table 4 Comparison of maximum diastolic potential of SA node, resting membrane potential of ventricular muscle, heart rate and some ECG parameters between human and rodents

From: A comparative review on heart ion channels, action potentials and electrocardiogram in rodents and human: extrapolation of experimental insights to clinic

Mammal

Parameters

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HR/min

PR interval/ms

QRS/ms

QTc/ms

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 ~ − 62

 ~ − 90

60–100

120–200

60–100

391–449, 459b

[58]

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 ~ − 65

range − 80–(− 90)

130–330

40–80

20–60

238–248

[59, 60]

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 ~ − 59

range − 80–(− 90)

192–338

55–78

53–75

264–265

[57, 65]

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 ~ − 58

range − 70–(− 80)

239–508

38–70

12–22

119–141a

[61, 64]

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 ~ − 58

range − 70–(− 80)

242–452

39–78

14–28

133–173

[61]

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 ~ − 60

range − 68–(− 80)

431–800

33.8–66.8

9.9–11.7

39.3–45.3

[62, 63]

  1. MDA, maximum diastolic potential of SA node; RMP, resting membrane potential; HR, heart rate; QTc, QT interval corrected by Bazett’s formula
  2. aQTc corrected by Fridericia formula
  3. b449 for male and 459 for female based Framingham formula
  4. c(Sprague–Dawley)
  5. d(Wistar)