Fig. 7
From: Zebrafish toxicological screening could aid Leishmaniosis drug discovery
Plot showing the means values ± IC95 of the number of spontaneous movements per minute of Danio rerio embryos 24 hpf exposed to different concentration of carbamazepine, benznidazole and 2-aminobenzimidazole derived. Images of well showing the results of spontaneous movement analysis performed on embryos with 24 hpf, submitted to DMSO (A) or treated with the compounds benznidazole 100 µM (B), carbamazepine 100 µM (C), and 2amnbzl-d 15 µM (D). The colored dots represent the movements performed by each embryo. These results were generated by the SOFTWARE ESPMOV Count v1.0 that analyzes the number of spontaneous movements from each embryo. The data were analyzed using ANOVA statistical tests and Dunnett's Multiple Comparison Test. (**) p < 0.001