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Fig. 1 | Laboratory Animal Research

Fig. 1

From: Reduced receptor for advanced glycation end products is associated with α-SMA expression in patients with idiopathic pulmonary fibrosis and mice

Fig. 1

Increased neutrophils and macrophages infiltrate in BLM-induced pulmonary fibrosis in mice. Mice were injected intratracheally BLM (1, 3 mg/kg) for 1 and 2 weeks. a Represented images showed lung fibrosis by H&E staining. b Macrophages and neutrophils were counted using Wright-Giemsa staining image of mice BAL cells (n = 2 per group). Macrophages were increased in 1 and 2 weeks. Neutrophils were dramatically increased in 1 week that injected BLM 3 mg/kg. Scale bar: 100-μm. *p < 0.05 and **p < 0.01 compared with CTL. IPF, idiopathic pulmonary fibrosis; BLM, bleomycin; CTL, non-treatment

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