Fig. 5

Venn diagram showing the four criteria for measuring acute lung injury in experimental animals, according to the official American Thoracic Society Workshop [7] in the reviewed publications. These criteria are measurement of inflammation, histological evidence of tissue injury, alteration of the alveolar capillary barrier and physiological dysfunction. Most often researchers measured histology, inflammation and pulmonary barrier results [24]. All four parameters were present in 15 of the 99 publications