Role of animal models in biomedical research: a review

Table 5 In vivo animal studies of different vascular grafts

Animal species	Type of graft	Graft diameter (mm)	Graft patency rate	In vivo study model	References
Ovine	EC-seeded xenogenic porcine decellularized carotid artery	5		Common carotid artery/external jugular vein arteriovenous shunt	[254]
Canine	PCL + VEGF	2	100% in 4 weeks	Femoral artery	[255]
Canine	P(LLA-CL) + Autologus, EC preendothelialization	4	88.9% in 24 weeks	Femoral artery	[256]
Canine	P(LLA-CL)	4	75% in 3 months	Femoral artery	[257]
Ovine	Decellularized graft derived from fibrin gel and ovine dermal fibroblasts	4	100% in 168 days	Carotid artery	[258]
Ovine	Heparin and VEGF-treated xenogenic porcine dSIS	5	92% in 90 days	Carotid artery	[259]
Mouse	PCL	0.5	53% in 28 days	Carotid artery	[260]
Rabbit	P(LLA-CL) + Collagen + Elastin + VEGF	4	86% in 3 weeks	Infrarenal aorta	[261]
Ovine	PCL electrospun + PLCL sponge	5	100% in 8 weeks	Carotid artery	[262]
Ovine	PHBV/PCL-GF	4	50% in 1 year	Carotid artery	[263]

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