Table 1 Characteristics of references enrolled in this Meta-analysis
Author | Year | Cancer types | Species, strain | Moulding method | Dosage | Adnimistration | Outcome | Score |
|---|---|---|---|---|---|---|---|---|
Wu.S | 2014 | Lung Carcinoma | C57BL/6 J,M,5-6w | LLC cells | – | – | TV | 7 |
Wistar rats, F, 5w | MNU induces | – | – | TV | 8 | |||
Algire.C | 2008 | SCID mice, F, 4-5w | MCF10AT cells | 50 mg/kg | p.o | TV | 7 | |
Seabloom.D | 2015 | Wistar rats | DEN induces | 12 mg/g | p.o | TN | 7 | |
Zhou.X | 2017 | Hepatocellular Carcinoma | SHR mice, F,6-8w | Fluka induces | 50 mg/kg | p.o | TV | 5 |
Tijeras-Raballand.A | 2020 | SHR mice, F,6-8w | Fluka induces | 150 mg/kg | p.o | TN | 6 | |
D.K. DePeralt | 2014 | C57BL/6 mice | melanoma cells SK-23 | 50 mg/kg | i.p | TW | 6 | |
Hsueh.E. C | 2013 | Melanoma | BALB/c nude | SW480 cells | 250 mg/kg | p.o | TV | 9 |
Takahashi.H | 2013 | Colon Cancer | athymic mice | LNCaP cells | 250 mg/kg | p.o | TV | 6 |
Madka.V | 2019 | C57BL/6 J mice, F, 6-8 W | OvCa cells | 70 mg/kg | p.o | TW | 6 | |
Litchfield.L. M | 2014 | Ovarian cancer | nude mice | human pancreatic cancer cells | 250 mg/kg | p.o | TV | 7 |
Mills.K. A | 2015 | athymic nude mice | SKOV3ip1 cells | 200 mg/kg | p.o | TN | 8 | |
Lengyel.E | 2015 | F344 rat, M,4-6w | azoxymethane-induced | 250 mg/kg | i.p | TN | 6 | |
Deriabina.O.N | 2010 | Skin Carcinoma | nude mice | PDX | 200 mg/kg | p.o | TV | 6 |
nu/nu athymic mice, F, 6w | PDX | - | - | TV | 7 | |||
Wei.L | 2019 | Prostate cancer | A/J mice, F, 7w | transgenic animal | 100 mg/kg | i.p | TN | 5 |
Hou.M | 2010 | nude mice | CFPAC-1 cell line | 50 mg/kg | p.o | TV | 6 | |
Cufí.S | 2013 | Mammary tumor | ApcMin/ + mice | transgenic animal | 250 mg/kg | p.o | TN | 8 |
Checkley.L.A | 2017 | C57BL/6, F, 5-6w | RENCA cells | 70 mg/kg | p.o | TV | 7 | |
Takahashi.M | 2015 | Renal carcinoma | LSL-KrasG12D/ + ;Trp53F2-10mice | transgenic animal | 50 mg/kg | p.o | TV | 6 |
Rajeshkumar.N.V | 2017 | Pancreatic Cancer | nude mice, M, 4-6w | HepG 2 cells line | 250 mg/kg | i.p | TV | 8 |
Kisfalvi.K | 2009 | C57BL/6 mice, M, 6w | pancreatic cancer cells | 250 mg/kg | p.o | TW | 7 | |
Cifarelli.V | 2015 | C57BL/6, M, 4-8w | RM-1 cells | 250 mg/kg | p.o | TV | 6 | |
Tan.X. L | 2015 | C57BL/6 | LLC cells | 250 mg/kg | p.o | TN | 7 | |
Shi.Y. Q | 2016 | nude mice, M, 4-6w | HepG 2 cells line | 200 mg/kg | p.o | TV | 8 | |
Fernandes.J.M | 2019 | Rectal Cancer | LKB1fl/flp53fl/fl mouse | ECC-1 and Ishikawa cells line | 250 mg/kg | i.p | TW | 6 |