Fig. 2
From: Humulus japonicus attenuates LPS-and scopolamine-induced cognitive impairment in mice
Effects of HJ on LPS-induced microglia activation in C57BL/6J mice. A, C Photomicrographs showing anti-Iba1 antibody-stained parietal cortex (A) and hippocampus (C). B, D Percent area occupied by Iba1 immunoreactivity in the parietal cortex (B) and hippocampus (D) in the vehicle + vehicle, vehicle + LPS, HJ200 (200 mg/kg HJ) + LPS, and HJ400 (400 mg/kg HJ) + LPS groups. E Fold change in mRNA expression of the IL-12 and IL-10 genes. *p < 0.05 and **p < 0.01, significant differences between indicated groups. ns, not significant. One-way ANOVA. Scale bar, 200 μm. Data are presented as the mean ± SEM