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Fig. 4 | Laboratory Animal Research

Fig. 4

From: Elucidating the characteristics of Mx1 and resistance to influenza A virus subtype H1N1 in the newly developed KWM/Hym mice

Fig. 4

Influenza A virus infection in the lungs of inbred BALB/c and KWM/Hym mice. BALB/c and KWM/Hym female mice were challenged intranasally with mouse-adapted A/WSN/1933 virus (H1N1, 1 × 105 pfu/mouse). Four days after infection, the lungs were collected and homogenized using a Tissue Lyser II. Virus titers were determined using a plaque assay in lung tissue homogenates. The experiment was performed in triplicates using the Madin-Darby Canine Kidney cells (N = 3/group). ***p < 0.0005

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