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Fig. 2 | Laboratory Animal Research

Fig. 2

From: Key factors to establish the ovalbumin-induced atopic dermatitis minipig model: age and body weight

Fig. 2

Histological analysis of skin layers in minipigs aged 12 months with 30 kg median body weight

Minipigs were treated with Ova during 2, 3, 4 weeks. (A–C) Masson’s trichrome staining. (A) Histology of skin layers from the epidermis to the subcutaneous. Green line: epidermis; Yellow line: dermis; SF: subcutaneous fat; HF: hair follicle; AG: apocrine gland. (B) Thickness of the epidermis. (C) Thickness of the dermis. p* < 0.05. (D-E) Immunohistochemistry. (D) E-cadherin; (E) Claudin-1. Scale bar = 100 μm; Ctl: control; Ova: ovalbumin

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