Fig. 5

Representative photomicrographs of the effect of Datura metel leaf extract on pyramidal cells of the hippocampus. A: VEH; B: DM (200 mg/kg); C: DM (400 mg/kg); D: DM (800 mg/kg);Plate A1–B4: Black arrow– shows sparsely packed pyramidal cells in the treated groups compared with control, red arrow: – shows sparsely packed granule cells in the treated groups compared with control plate B1–B4: Black Arrow– pyramidal cells, red arrow—granule cells; yellow arrow – nuclear pyknosis, blue arrow- cell body chromatolysis. H and E stain, Mag: × 40, × 250; Calibration bar for all figures = 0.01 mm (10 µm). VEH Vehicle, DM Datura metel